Now showing items 1-4 of 4

    • Bieler, Sylvain; Estrada, Lisbell D.; Lagos Mónaco, Rosalba; Baeza Cancino, Marcelo; Castilla, Joaquín; Soto, Claudio (AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2005-07-22)
      The aggregation of proteins into amyloid fibrils is the hallmark feature of a group of late-onset degenerative diseases including Alzheimer, Parkinson, and prion diseases. We report here that microcin E492, a peptide ...
    • Morales Zavala, Francisco; Casanova Morales, Nathalie; Gonzalez, Raúl B.; Chandia Cristi, América; Estrada, Lisbell D.; Alvizu, Ignacio; Waselowski, Víctor; Guzmán, Fanny; Guerrero, Simón; Oyarzún Olave, Marisol; Rebolledo, Cristian; Rodríguez, Enrique; Armijo, Julien; Bhuyan, Heman; Favre, Mario; Alvarez, Alejandra R.; Kogan Bocian, Marcelo; Maze, Jerónimo R. (BMC, 2018)
      Background: Stable and non-toxic fluorescent markers are gaining attention in molecular diagnostics as powerful tools for enabling long and reliable biological studies. Such markers should not only have a long half-life ...
    • Morales, Rodrigo; Estrada, Lisbell D.; Díaz Espinoza, Rodrigo; Morales Scheihing, Diego; Jara, María C.; Castilla, Joaquín; Soto, Claudio (2010-03-31)
      The central event in protein misfolding disorders (PMDs) is the accumulation of a misfolded form of a naturally expressed protein. Despite the diversity of clinical symptoms associated with different PMDs, many similarities ...
    • Soto, Claudio; Estrada, Lisbell D. (American Medical Association, 2008-02)
      Akey molecular pathway implicated in diverse neurodegenerative diseases is the misfolding, aggregation, and accumulation of proteins in the brain. Compelling evidence strongly supports the hypothesis that accumulation ...